Maria is now part of a continuum of care complex known as the Dominican Life Center. It includes the Regina residence, which was originally build in 1960 to house Academy students and later became apartments for Sisters. The most recent addition is St. Catherine Chapel, dedicated in 2003.
In 1968, Weber Hall replaced the Old North Building as the Congregation’s novitiate. A few years later, it was re-dedicated as the Weber Retreat and Conference Center.

The grounds of the Motherhouse campus include the Weber Circle Garden (1996), an outdoor Chartres-style labyrinth (2000), the Cosmic Walk and Nature Path (1999), and wetlands (2001) which became a pond (2024). Both Roncalli and Ratisbon were deconstructed in 2024. A new building is being constructed adjacent to Holy Rosary Chapel that will house the Congregation archive and gallery exhibits that share the history of the Adrian Dominican Sisters and invite people to learn more about the Dominican Charism.
Permaculture design is used on natural areas of the campus with an eye toward long term sustainability of the land that has sustained the Adrian Dominican Sisters.